β-Adrenoceptor antagonists (class II)
Clinical uses of class I antidysrhythmic drugs
• Class Ia (e.g. disopyramide)
o ventricular dysrhythmias
o prevention of recurrent paroxysmal atrial fibrillation triggered by vagal overactivity.
• Class Ib (e.g. intravenous lidocaine )
o treatment and prevention of ventricular tachycardia and fibrillation during and immediately after myocardial infarction.
• Class Ic
o to prevent paroxysmal atrial fibrillation (flecainide)
o recurrent tachyarrhythmias associated with abnormal conducting pathways (e.g. Wolff-Parkinson-White syndrome).
Clinical uses of class II antidysrhythmic drugs (e.g. propranolol, timolol )
• To reduce mortality following myocardial infarction.
• To prevent recurrence of tachyarrhythmias (e.g. paroxysmal atrial fibrillation) provoked by increased sympathetic activity.
Clinical uses of class III antidysrhythmic drugs
• Amiodarone: tachycardia associated with the Wolff-Parkinson-White syndrome. It is also effective in many other supraventricular and ventricular tachyarrhythmias but has serious adverse effects.
• (Racemic) sotalol combines class III with class II actions. It is used in paroxysmal supraventricular dysrhythmias and suppresses ventricular ectopic beats and short runs of ventricular tachycardia
Adenosine (unclassified in the Vaughan Williams classification)
Clinical uses of class IV antidysrhythmic drugs
• Verapamil is the main drug. It is used:
o to prevent recurrence of paroxysmal supraventricular tachycardia (SVT)
o to reduce the ventricular rate in patients with atrial fibrillation, provided they do not have Wolff-Parkinson-White or a related disorder.
• Verapamil was previously given intravenously to terminate SVT; it is now seldom used for this because adenosine is safer.
Friday, October 01, 2010
Home »
» ANTIARRHYTHMIC DRUG SCHEME
ANTIARRHYTHMIC DRUG SCHEME
Related Posts:
What is Gastroesophageal Reflux Disease? Causes, Diagnosis and TreatmentGERD, also known as gastroesophageal reflux disease, is a condition wherein the contents of the stomach are being regurgitated back up the esophagus. Because of the acidity of the contents of the stomach, the lining of the es… Read More
The anorexic mom who wears the same cloths as her 7-yr-old daughterStanding side-by-side in matching outfits, you'd be forgiven for mistaking Rebecca and Maisy Jones as sisters. But, in fact, this is a picture of a 26-year-old woman and her seven-year-old daughter. After suffering from anore… Read More
Head patch watches over stroke patients’ blood flow in brainsStroke is one of the silent killers just like heart attacks, and the amount of damage it does to the body varies, with many of those who suffered from a stroke before having to live with limited movement as well as slurred sp… Read More
Pupils who shout out in class achieve better results than their counterpartsImpulsive children who find it irresistible to shout out in class score higher in tests than their peers, who seem to be better behaved and quiet, state researchers.A Durham University study that looked at 12,000 primary scho… Read More
What is Restless Leg Syndrome? Causes, Diagnosis and TreatmentA lot of us may not consider restless leg syndrome (RLS) as a serious condition, but for those who are affected, it is a different story. Restless leg syndrome, or Willis-Ekburn disease, is a condition that is neurological in… Read More
0 comments:
Post a Comment