Mostly asked Pathology Multiple choice Questions (MCQs)

Answers are given at the end of this post

51. Most common cause of calcium oxalate stone formation

A)Hyperuricosuria

B)hypercalciuria without hypercalcemia

C)Hypercalcemia and hypercalciurea

D)Hyperoxaluria

E)Hypocitraturia



52. Which of the following is benign lesion of the brain

A)Anaplastic astrocytoma

B)Fibrillary astrocytoma

C)Gemistocytic astrocytoma

D)Glioblastoma

E)Pilocytic astrocytoma



53. False regarding medulloblastoma is

A)Predominantly occur in childhood

B)Occur in cerebrum

C)Has a desmoplastic variant

D)Highly malignant

E)Radiosensitive


54. False regarding global cerebral ischemia

A)Coagulative necrosis occur

B)Brain is swollen gyri widened and sulci narrowed

C)There is selective vulnerability

D)Repair occur after 2 weeks

E)Flat EEG is possible in some cases



55. Papillary dilation and disturbed ocular movements is feature of

A)Submachine herniation

B)Transtentorial herniation

C)Tonsillar herniation

D)Hydrocephalus

E)Tubal defect



56. A tumor found attached to dura membrane, which consists of elongated

cells, psammoma bodies most probably, it is

A)Astrocytoma

B)Medulloblastoma

C)Meningioma

D)Ependyoma

E)Pilocytic astrocytoma



57. A 60 years old patient, with signs of meningitis CSF shows low glucose,

high proteins, leucocytes, causative organism would be

A)Streptococcus pneumonia

B)N meningitidis

C)Listeria

D)E coli

E)H influenza



58. Difference b/w anaplastic astrocytoma and glioblastoma, glioblastoma

shows

A)Palisade pattern of necrosis

B)Endothelial proloiferation

C)Does not resemble anaplastic astrocytoma very much

D)Is not a malignant

E)Occurs in meninges



59. The gene not affected in Alzheimer disease is on

A)Chromosome 21

B)Chromosome 14

C)Chromosome 1

D)Chromosome 2

E)Chromosome 19



60. Age group having 40% incidence of Alzheimer’s disease is

A)70-75 yrs

B)60-65 yrs

C)80-84 yrs

D)80-89 yrs

E)55-60 yrs



61. False regarding neurosyphilis

A)is a secondary stage of disease?

B)tabes dorsalis is a feature

C)charcot joints are associated

D)meningovascular neuro syphillis is major presentation

E)all of these are correct



62. The commonest cause of cerebral hemorrhage is

A)Hypertension

B)Trauma

C)Berry aneurysm

D)Vascular malformation

E)Emboli



63. Intra nuclear and intra cytoplasm inclusions are found in infection of

A)Herpes

B)Rabies

C)Alzheimer’s disease

D)CMV

E)Parkinson disease



64. Paraneoplastic syndrome not associated with small lung cell Ca

A)Stiffen syndrome

B)Lambert Eaton syndrome

C)Cerebrellar degeneration

D)Retinal degeneration

E)Sensory neuropathy



65.Which is not a route of CNS infection

A)Haematogenous spread

B)Direct implantation

C)Local extension

D)Peripheral nervous system

E)Lymphatic spread


66.Most common ovarian Ca

A)serous cyst adenocarcinoma

B)serous cyst adenoma

C)mucinous CA

D)malignant teratoma

E)clear cell CA



67.Stroke frequently occur in the territory of which of the following artery

A)Posterior cerebral artery

B)Internal carotid artery

C)Middle cerebral artery

D)Anterior cerebral artery

E)Basilar artery



68. subacute combined degeneration of the spinal cord is usually associated

with which of the following vitamin deficiency

A)Vit B1

B)Vit B2

C)Vit B6

D)Vit B12

E)Vit C



69.Which of the following is the common malignancy of the CNS

A)Astrocytoma

B)Medulloblastoma

C)Glioblastoma

D)Ependyoma

E)Pilocytic astrocytoma



70. Regarding Teratoma testis

A)5-10 cm in diameter

B)Occurs in adults

C)May occur at any age

D)Shows hemorrhage and necrosis

E)Constitute about 5-10% of germ cell tumors in adults



71. Teenager, sever pain around knee, relieved by aspirin

A)Osteoid osteoma

B)Chondrosarcoma

C)Chondroma

D)Osteoma

E)Osteoblastoma


72. Multinodular cysts full of gelatinous material seen in ovary will show cell

differentiation of

A)Tall columnar epithelium

B)Tall columnar ciliated epithelium

C)Squamous epithelium no keratinizing

D)Squamous epithelium

E)Tall columanr serous epithelium



73. The most common vaginal congenital anomaly is

A)Gartner duct cyst

B)Double uterus

C)Mucous cyst

D)Septate vagina

E)Ateria



74. Regarding follicular cervicitis, it occurs in infection of

A)Chlamydia trachomatis

B)N gonorrhoeae

C)Trichomonas

D)HPV

E)Herpesvirus



75. C. trachomatis will cause

A)follicular cervicitis

B)strawberry cervix

C)sq cell CA of cervix

D)wart formation

E)paget disease



76. A patient with high B.P and proteinuria during pregnancy, condition

relieved after delivery, morphologically there will be

A)Multiple infarcts in placenta

B)Sheehan syndrome

C)Hydatidform mole

D)Choriocarcinoma

E)Trophoblastic tumour



77. The most important risk factor for cervical cancer

A)Early age at first intercourse

B)Persistent infection with HPV

C)multiple sexual partners

D)Oral contaceptives

E)Genital infections


78. A female with dysperonia, dysmenorrheal, diffuse hypertrophy of uterus

not palpable on clinical exam, the probable diagnosis is

A)Endometrial hyperplasia

B)Adenomyosis

C)Endometriosis

D)Polyp

E)Leiomyoma



79. The serous cystadenoma of ovary, histologically will resemble to

A)Endometrium

B)Fallopian tube

C)Cervix

D)Vagina

E)None of these



80. A fetus born with grapes like structure coming out from vagina she is

having

A)Polyp

B)Vagianal prolapse

C)Embryonal rhabdomyosarcoma

D)Strawberry cervix

E)Adenocarcinoma



81. Regarding leiomyoma

A)65% occur in reproductive age

B)No chromosomal abnormality is linked

C)most common uterine tumor

D)is a consequence of PID

E)malignant in nature



82. Which of the following has great bleeding tendency?

A)Endometrial hyperplasia

B)Adenomyosis

C)Endometriosis

D)Polyp

E)Leiomyosarcoma



83. Endometrial hyperplasia is linked with

A)RAS gene mutation

B)PID

C)Estrogen replacement therapy

D)Teratoma of ovary

E)EPTN gene mutation


84. Kilocytic atypia seen in pap smear is indicative of

A)HPV

B)Chlamydia trachomatis

C)N gonorrhoeae

D)Trichomonas

E)Herpesvirus



85. Primary site of krukenberg tumor

A)Stomach

B)Ovaries

C)Pancreas

D)Breast

E)Liver



86. Most common tumor differentiation in dermoid cyst is into

A)Thyroid carcinoma

B)Melanoma

C)Basal cell CA

D)SQ. cell Ca

E)serous tumor of ovary



87. Beside breast another site of hidroadenoma is

A)Vagina

B)Cervix

C)Endometrium

D)Fallopian tube

E)vulva


88. The most common histological variant of breast cancer

A)Colloid carcinoma

B)Pagets disease

C)Lobular carcinoma

D)Medullary carcinoma

E)Ductal invasive carcinoma



89. In fibrocystic change the most likely group of histological findings is

A)Adenosis with atypical lining epithelium

B)Apocrine metaplasia cyst formation and fibrosis

C)Cyst formation inflammation and carcinoma in situ

D)Papillary proliferation of ductal epithelium with atypia

E)Proliferation of ducts surrounded by dense fibrosis


90. Ductal papilloma mostly occur in

A)Nipple and areola

B)Chest wall and ribs

C)Lobular stroma

D)Terminal ducts

E)Lactiferous ducts



91. A female has rubbery tan mass of 2 cm in her right breast she is having

A)Fibroadenoma

B)phylloid tumor

C)ductal papilloma

D)medullary carcinoma

E)tubular carcinoma



92. If a tumor of breast has many estrogen receptors, it implies

A)It is bad prognostic feature

B)Is about to metastasize

C)Proliferate rate is very high

D)Karyotype is normal

E)good response to tamoxifen



93. Difference between phylloid tumor and fibroadenoma is that phyllois tumor has

A)hypercellurity and stromal over growth

B)rarely metastasize

C)is very common

D)is identical to ductal invasive CA.

E)none of these



94. Regarding histology of gynaecomastia

A)Mucosal plugging is present

B)Hyalinization and fibrosis is not a feature

C)Frequently develop into carcinoma

D)Proliferation of fatty tissues occur

E)ductal hyperplasia and edema



95. Toxic ATN is manifested mostly in

A)PCT

B)DCT

C)Collecting ducts

D)Glomerulus

E)Ducts of bellin


96. In the recovery phase of ATN the main electrolyte problem is

A)Hyperkalemia

B)Hypokelemia

C)Hyponatremia

D)Hypernatremia

E)Hypercalcemia



97. Choriocarcinoma second most commonly metastasize to

A)Liver

B)Lungs

C)Cervix

D)Vagina

E)Kidneys



98. Mumps orchitis is

A)Bilateral

B)Sterility is common complication

C)Simultaneously with parotid swelling

D)Occurs in infants

E)Infection reaches via haematogenous spread



99. Not elevated in diabetes dyslipedemia

A)HDL

B)triglycerides

C)c- reactive proteins

D)small dense LDL

E)cytokines



100. Regarding Stye,all are correct, except

A)Acute suppurative inflammation of zeis gland

B)Factor is poor hygiene

C)Leads to granuloma formation

D)S.aureus is the organism

E)Called external hordeolum

ANSWERS:

51-B)

52-E)

53-B)

54-A)

55-B)

56-C)

57-A)

58-B)

59-D)

60-C)

61-A)

62-A)

63-D)

64-A)

65-E)

66-A)

67-C)

68-D)

69-C)

70-E)

71-A)

72-A)

73-A)

74-A)

75-A)



















76-B)

77-B)

78-B)

79-B)

80-C)

81-C)

82-D)

83-C)

84-A)

85-A)

86-D)

87-E)

88-E)

89-B)

90-E)

91-A)

92-E)

93-A)

94-E)

95-A)

96-B)

97-D)

98-E)

99-A)

100-C)