A 67-year-old retiree was employed for many years in the plastics industry where he was exposed to vinyl chloride. This industrial exposure has increased his likelihood of developing which of the following?
(A) focal nodular hyperplasia
(B) hepatic adenoma
(C) hepatic angiosarcoma
(D) hepatic fibroma
(E) hepatocellular carcinoma
Answer:
C:
Environmental exposure to vinyl chloride is associated with the later development of hepatic angiosarcoma. Focal nodular hyperplasia (choice A) and hepatic fibroma (choice D) do not at present have well-defined antecedent environmental exposure histories. Hepatic adenomas (choice B) occur sporadically in the setting of exogenous steroid hormone usage. Hepatocellular carcinoma (choice E) is associated with cirrhosis, chronic viral hepatitis, and aflatoxin exposure.
(A) focal nodular hyperplasia
(B) hepatic adenoma
(C) hepatic angiosarcoma
(D) hepatic fibroma
(E) hepatocellular carcinoma
Answer:
C:
Environmental exposure to vinyl chloride is associated with the later development of hepatic angiosarcoma. Focal nodular hyperplasia (choice A) and hepatic fibroma (choice D) do not at present have well-defined antecedent environmental exposure histories. Hepatic adenomas (choice B) occur sporadically in the setting of exogenous steroid hormone usage. Hepatocellular carcinoma (choice E) is associated with cirrhosis, chronic viral hepatitis, and aflatoxin exposure.
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